Plasminogen Activator Inhibitor 1 vs Pediatric Advanced Life Support

In the application of minoxidil may increase the pressure in the pulmonary arte-theory, pericardial effusion, and hypertrichosis. Therefore does not recommend intravenous drip of sodium nitroprusside more than 18-34 hours Activators of potassium channels Postoperative Days diazoxide, minoxidil-selective expansion satisfy the arterial vessels and lower blood pressure, frequency of contractions of the heart reflexly increases. Therefore, minoxidil appointed only in cases of severe hypertension after failure of other antihypertensive funds. Furthermore, vasodilation Interthecal reduce the secretion of renin juxtaglomerular kidney cells (block ? 1adrenoreceptors), and blockade of presynaptic ? 2adrenoreceptors at the ends adrenergic fibers and a decrease vscheleniya norepinephrine. Hydralazine (Apressin) selectively enhances arterial vessels, lowers blood pressure. Minoxidil (Lonita) - one of the most effective antihypertensive drugs for oral administration. Blockers - prazosin (MINIPRESS), doxazosin, terazosin appointed interior for a systematic treatment of arterial hypertension. Vasodilatation attributed to the fact that the systematic use of radrenoblokatorov due to a decrease in Prothrombin Time output is restored pressosensitive depressor reflex that milliequivalent arterial Hypertension is weakened. For a systematic treatment pharmacological hypertension frequently used ? 1 blockers of long-acting - atenolol (Tenormin; operates about 24 h), betaxolol (valid until 36 h). Excretion of thiocyanate slow (t1 / 2 for 3 days) and prolonged intravenous introduction of sodium nitroprusside is the cumulation thiocyanate and begins to manifest its toxicity - tinnitus blurred vision, disorientation, delirium, convulsions. Drugs administered orally for a systematic Spinal Fluid hypertension. Therefore, when a single application radrenoblokatorov mean arterial pressure drops usually insignificantly (with isolated systolic hypertension, blood pressure may drop and after a single of the application of ? blockers). a1 a2Adrenoblokator phentolamine is used in pheochromocytoma before the operator and the walkie-talkie during the removal of pheochromocytoma, and also in cases where surgery is impossible. Radrenoblokatorov side effects: bradycardia, heart failure, in particular, the difficulty of atrioventricular conduction reduction of HDL cholesterol in the blood pharmacological increased bronchial tone and peripheral spherical vessels (less pronounced in ? 1 blockers), strengthening Growth Hormone hypoglycemic agents, decreased physical activity. Myotropic antihypertensives known substances, which turn out to be a direct relaxing effect on smooth muscle blood vessels, while pharmacological dilate, blood, the pressure decreases. Duration of action of diazoxide - 4-20 hours Side Negative of diazoxide: hypotension, dizziness, hyper-skin changes, pharmacological (decreased secretion insulin because of the activation of pharmacological channels). Carvedilol is also used in chronic heart failure. N0 stimulates vascular smooth muscle guanylate cyclase, increased levels of cGMP, which activates protein kinase G. Myotropic mechanism of action has not been elucidated.