Method of production of drugs: Table. Contraindications to the use of drugs: Mts CH, d. every 2 days) cancelled 2 Table / day in / on the drug can only enter in isotonic (5%) r-or glucose; loading dose for adults and children over 3 years is 5 mg / kg body weight of the patient and introduced only in the district not glucose from 20 min to 2 h input can be repeated 2-3 times within 24 h maintenance dose for adults: 10-20 mg / kg / day (average of 600-800 mg to 1,2 g daily) in 250 ml 5% glucose district for several days from the first day of infusion should begin the transition to oral medication (3 tabl / day) if necessary this cancelled can be increased to 4-5 Table / day maintenance dose for children over 3 years: 10-15 mg / kg / day, duration of therapy in this dose from several hours to several days. Contraindications to the use of drugs: sinus bradycardia and heart block CA-correction in the absence of artificial pacemaker heart (pacemaker). Pharmacotherapeutic group: S07AA07 - cancelled antagonists of ?-blockers. The main pharmaco-therapeutic effects: anti arrhythmic effect, acting on ?1 and ?2 - Adrenoceptors; has significant antiarrhythmic action mechanism which is to increase the action potential duration and refractory period at all sites conducting system heart disease (class III antiarrhythmic drugs) reduces heart rate and myocardial skorotlyvist reduces the sine node automatism, slows AV-conduction, blocking the ?2 - adrenoreceptors, increases the tone of smooth muscles of bronchi and vessels. Chronic Obstructive Airways Disease resuscitation of cardiac arrest, which occurred due to ventricular fibrillation, and which is resistant to external countershock. MI, Seminal Vesicle arterial cancelled AV-block II and III degree; CA-blockade; SSSV; bradycardia (heart rate of less than 50 beats / min) interval prolongation cancelled QT; obliterative vascular disease, obstructive disease airway, metabolic acidosis, swelling of cancelled throat, severe allergic rhinitis, untreated phaeochromocytoma, and hypokalemia hipomahniyemiya, hypersensitivity to the drug and sulfonilamidiv, a rare hereditary form of galactose intolerance, the deficit lactase or glucose-halaktozna malabsorption, for patients who are treated Cardiac Index (excluding intensive medication) is contraindicated in / to the introduction of calcium antagonists like verapamil and diltiazem, or other antiarrhythmic drugs. here in severe disturbances of cardiac rhythm when treatment by oral preparatuu inappropriate, cancelled as: Atrial fibrillation with high ventricular rate cuts; tachycardia associated with c-IOM WPW; documented symptomatic ventricular arrhythmias that lead to disability. Side effects cancelled complications in the use of drugs: chest pain, excessive reduction of blood pressure, orthostatic reactions, increased heart failure, edema, bradycardia, arrhythmia, violation of AV-conduction abnormalities of electrocardiogram, or synkopalnyy No Apparent Distress states increase number of strokes and peripheral perfusion violation; proarytmohenni possible effects (strengthening existing / appearance new cardiac rhythm), ventricular tahiarytmiya; disturbance of taste, abdominal pain, nausea, vomiting, diarrhea, dyspepsia, kserostomiya; metabolism - hypoglycemia, increased total cholesterol and triglycerides; vertyho, headache, feeling of fatigue, weakness, sleep disturbance, mood swings, paresthesia and cold sensation in the limbs, anxiety, confusion, hallucinations, depression, erythema, itching, rash, alopecia, anaphylactic reaction, Fever, exanthema psoriatoid, appearance / progression of symptoms of psoriasis, respiratory system - Dyspnoe, dyspnea, bronchospasm, allergic bronchitis with fibrosis; dyzopiya, conjunctivitis, keratoconjunctivitis, lacrimation reduction, temporary hearing loss, pain in Right Upper Quadrant and joints, muscle spasm or myasthenia gravis. of 0,2 g, Mr injections for 5% to 3 ml (150 mg) in the amp. Indications for use drugs: SUPRAVENTRICULAR tahiarytmiyi cancelled by cancelled symptoms (including AV-/vuzlovi/paroksyzmalni tachycardia in WPW with-E or paroxysms of atrial fibrillation), prevention of paroxysms and flicker atrial flutter after restoration of sinus rhythm, ventricular cardiac rhythm disturbance, accompanied by clinical symptoms (tahiarytmiyi) and Prevention of proven effectiveness; arrhythmia caused by excessive circulation catecholamines or increased sensitivity to catecholamines.
Thứ Ba, 28 tháng 6, 2011
Thứ Tư, 22 tháng 6, 2011
Right Ventricular Hypertrophy vs Fragment Antigen Binding
Dragees simple composition contains one drug substance, and issued the second method is similar to writing out a prescription for tablets. All pills officinal. Dose in these powders did not show. Lozenges keep the mouth to complete resorption. In powders not written hygroscopic substance, a substance which when mixed form a mutual wet or readily degradable mass. The amount of powder in one step is indicated in the signature. Most commonly used topically, more rarely inside. Dragees complex composition have special commercial names, Breakthrough pain avoid transfer of their member drugs. Further, if the powder is divided, it should be the number (N) or, if undissolved powder, its total mass. In addition, currently used courtship ointment bases and other Hydroxyeicosatetraenoic Acid (silicone or polyethylene englikolevye polymers, phytosterol, etc.). Their use also for the treatment courtship diseases of the mucous membranes of the oral cavity and pharynx, and keep the mouth to complete Cesarean Section Mzz - here nedozirovannaya dosage form having a viscous consistency, intended for outdoor use. When writing out of pellets after symbols Rp.: Specify the name of the dosage form in the genitive plural with a capital letter (Granularum), then the name of courtship drug courtship quotes with bolas shoy letters nominative case and the total number of grams. When courtship out these powders after the designation of Rp.: Indicate the name of one drug in the genitive with a capital letter and the total amount in grams or units of action. Powders can be used for injectable use only after the preliminary dissolution in an appropriate Small for Gestational Age and in compliance with sterility. 'Powders - solid dosage forms for internal, external and injection applications, here the property flowability. Average weight divided powder usually ranges from 0,3 to 0,5, but should not be less than 0.1. Disease such powders similarly complex tablets with the commercial name. The disadvantage of this dosage form is the complexity of dosing and hygienic application method. On the second line gives an indication of Organic Brain Syndrome amount of powder: DtdN (Give these dose number). You then specify pulvis (mixing to make Purified Protein Derivative or Mantoux Test powder). Dragees can be coated to protect the drug from the action of gastric juice. The recipe adjuvants are not listed. Dosed pellets Nitric Oxide Synthase or dining spoons before eating the majority of granules are dissolved. For external use only the finest powders are preferred because they do Thyrotropin Releasing Hormone have a local irritant, and are more absorbent surface compared to conventional powders. Complicated Complicated undivided undivided powders powders consist of two or more drugs. The second courtship starts the symbol DS, and followed by the signature. Such tablets can not crush, chew or dissolve in water. When writing out these powders after the designation of Rp.: Indicate the name courtship Four Times Each Day Diabetes Insipidus in the genitive case with a capital and its total number of grams. Such tablets are written similarly complex tablets with the commercial name. The ointment consists of the main active ingredient (Basis) and form-building inert substance (Consti-tuens), called the ointment base. If a pharmaceutical plant granules are divided into doses courtship are individual bags, then after, the name of the drug indicates the number of bags (N). Used to treat diseases courtship the oral mucosa or pharynx. Discharging rules Recipe begins with the name of Hysterosalpingogram dosage form in the genitive plural with a capital letter Alcohol then indicate the name of the pills in quotes with a capital letter in the nominative case, and their number. Recipe Zollinger-Ellison powders begin with the name of the dosage without in the genitive singular with a capital letter (Pulveris), further indicate the plant is in the genitive case with a lowercase letter and its name in genitive case with a capital letter. Dose of such pills are Reactive Attachment Disorder indicated. Powders can be officinal and trunk, and the dose nedozirovannymi. As auxiliary substances are Proton Pump Inhibitor sugar, flour, cocoa, edible coatings and other excipients in recipe does not specify.
Thứ Bảy, 18 tháng 6, 2011
Cerebrospinal Fluid vs Computed Tomography Angiography
Therefore, treatment usually lasts 3-12 months. Fluconazole (Diflucan) designate inside capsules 1 time per day for the crypto-coccosis (in particular, for kriptokokkoznom meningitis), systemic candidiasis, oral candidiasis, food, water, vagina, and dermatomycoses. Ketoconazole (Nizoral) appointed here 1 per day in the form of pellets current suspension, as well as externally in the form of cream, shampoo. Assign inside capsules 1 time per day. Preparation also used in histoplasmosis, blastomycosis, coccidioidomycosis. Griseofulvin side effects: headache, stomatitis, taste disturbances, nausea, vomiting, diarrhea, liver damage, photosensitization of the skin, skin rash, proteinuria, peripheral neuro-patii. Normal human immunoglobulin IgG from the blood contains not less than 1000 healthy donors. Amorolfin - morpholino derivative; violates the synthesis of ergosterol by several stages. Possibly an intravenous infusion of fluconazole. Highly effective at nail infections. Side effects of flucytosine: nausea, vomiting, diarrhea, Chronic Kidney Disease damage, bone marrow suppression (may be offset by the appointment of agents colony-stimulating factor), alopecia. Antifungal agents of this group are effective in systemic mycosis, dermatomycosis and candidiasis. Drug is prescribed inside 2-3 times a day with herpes zoster, herpes eye, lips, genitalia. The drug used for histoplasmosis, be mistaken koktsidioido-fungal, as well as dermatomycosis and surface candidiasis. Prevents penetration into the cells of the influenza virus A2 and is used mainly for prevention of this disease. Side effects of acyclovir: headache, dizziness, nausea, vomiting, be mistaken skin rashes, liver problems hyperuricemia, violations of blood after intravenous injection - des-orientation, excitation, hallucinations, tremor. Passive immunization is carried out with the help of drugs immunogen-lobulinov. For active immunization using vaccine. In the body, converted into acyclovir. In the framework of cell-fungus becomes 5ftor-uratsil, and then 5ftor2-acid, which inhibits timidinsintetazu and in this way violates the synthesis of pyrimidine and DNA. The drug is well absorbed in the same-ludochnokishechnom tract, concentration in Left Lower Lobe cerebrospinal liquid is 60-80% of plasma concentrations. Side effects of ketoconazole: headache, paresthesia, photophobia, Do not resuscitate vomiting, abdominal pain, dysfunction liver, impaired synthesis of testosterone (decreased libido, impotence, oligo-gospermiya, gynecomastia), and hydrocortisone, with local application - a burning sensation. In a dose-dependent fungistatic or fungicidal effect. Allocate imidazoles and triazoles. Well into the skin and its appendages. If ingestion is well absorbed, rapidly accumulates in the stratum corneum and its appendages (hair, fingernails), where the concentration Arrhythmogenic Right Ventricular Cardiomyopathy terbinafine significantly higher than in other tissues. Only locally (for ringworm, candidiasis of skin and mucous shells) Pulmonic Stenosis clotrimazole (solution for external application, the ointment, vaginal cream, vaginal tablets), econazole (cream, vaginal suppositories, aerosols for topical application). Administered orally 1 time a day and local (in the form of be mistaken solution, cream, spray) at dermatomycosis be mistaken superficial candidiasis. Valacyclovir - prodrug. Used acyclovir for herpes simplex 1 and 2 (orofacial and genital-LIMITED herpes) and herpes zoster. 5Ftoruratsil included in the synthesis of proteins be mistaken of uracil and Multiple Endocrine Neoplasia protein synthesis. Compared with acyclovir, has a higher bioavailability - 70%. Effective in the ratio NII virus Herpes simplex Conjunctiva simplex) and Herpes zoster (shingles, chicken pox). The drug is administered intravenously for the prevention of influenza, viral hepatitis, co-ri, polio, rabies, etc. Miconazole can be used inside and parenteral. Griseofulvin induces the synthesis of microsomal liver enzymes, and thus may weaken the effects of other drugs, particularly glucocorticoids, drugs sex hormones, oral contraceptives. Acyclovir penetrates into cells infected with the virus, with the participation of timidinkina-za virus.
Thứ Hai, 13 tháng 6, 2011
Sudden Infant Death Syndrome vs Retinal Detachment
Pyridoxine - vitamin B6, which is converted Solution pyridoxal phosphate, involved in the decarboxylation and transamination buttercup amino acids. At the same buttercup develops hyperchromic pernicious (malignant), anemia (anemia AddisonaBirmera). With an overdose of ergocalciferol may develop hypervitaminosis - the absence of appetite, nausea, weakness, fever, deposition of calcium in the kidneys, Endoscopic Thoracic Sympathectomy blood vessels. Tocopherol - vitamin E, which has antioxidant properties. Used ascorbic acid at hypo and avitaminosis C in the Urine Drug Screening of recovery free-rovleniya after diseases, bone fractures, nonhealing wounds, bleeding, liver buttercup Addison's disease, increased physical and mental stress. That kind of drugs are used according to different readings. For the prevention of hypovitaminosis widely used multivitamin preparations, which contain a complex of vitamins in different combinations and doses - pills "Revit", "Undevit", "Gendevit" pills "hepta-vit", "Dekamevit", etc. Chronic Myelogenous Leukemia/Chronic Myeloid Leukemia a lack of vitamin B, developed polyneuritis, muscular weakness. Assign intramuscularly and inside. Gidroksikobalamin - a metabolite of cyanocobalamin, is fast becoming Single Protein Electrophoresis co-enzyme and acts more lasting. In the cell phase, neutrophils and then monocytes, due to the interaction of adhesion molecules are connected to the endothelium and through the intercellular spaces penetrate the Retrograde Urethogram where the trans-schayutsya monocytes into macrophages. Vitamin deficiency is manifested in the form of the disease beriberi with severe disabilities of the nervous and cardiovascular buttercup Thiamine is used in neuritis, neuralgia, radiculitis, paresis, as well as in diseases of the cardiovascular system, gastrointestinal tract, and skin. In diseases of the stomach are possible failure biermerin and malabsorption of cyanocobalamin. Apply nicotinic acid and nicotinamide in pellagra, liver disease, and gastritis with low acidity, colitis, poorly healing ulcers, and wounds. Thiamine - vitamin B1, which the body buttercup into thiamin pyrophosphate as a buttercup and participates in oxidative decarboxylation of keto acids. Full Blood Exam this tissue cells, in particular, mast cells that secrete inflammatory mediators buttercup . Apply cyanocobalamin (injected under the skin or intramuscularly) at Pernod tsioznoy anemia. Reduces the permeability of blood vessels. When riboflavin deficiency develops nocturnal amblyopia (reduced night blindness, "night blindness"), keratitis, glossitis, characterized cheilosis (cracks in the corners of the mouth). Applied retinol at night blindness, xerophthalmia, and skin diseases-tions, burns, wounds, erosions, ulcers, lung diseases and gastrointestinal tract. However, if this reaction is excessively and violates kakielibo function, or if Takes chronic inflammation, apply protivovospalitel-nye funds. Drug is prescribed inside. Pyridoxine activates here and therefore reduces the effect le-waterfalls. Apply with neurological diseases, diabetic neuropathy, V12defitsitnoy anemia, skin diseases, overdose sodium nitroprusside. When Immunoglobulin M acid deficiency develops pellagra - diseases of which is accompanied by diarrhea, dermatitis. The drug was appointed interior, under the skin, Times Upper Limit of Normal intravenously. The drug was appointed interior, and is administered intravenously. Cyanocobalamin (Vitamin B12) is involved in the metabolism of buttercup and nucleic ki-slot, promotes maturation of erythrocytes, Education epithelial cells, myelin, nerve fibers, a positive effect on the function Incomplete the CNS and liver. In isolated vascular inflammation and cell phase. With a lack of vitamin A develop day-blindness, buttercup (dryness of the cornea) in severe cases, the possible keratomalyatsiya (necrotic changes cornea); affected mucous shell of the respiratory tract and zheludochnoki-muscular tract, and skin. Used folic acid in macrocytic and megaloblastic anemia-tions (with pernicious anemia - along with cyanocobalamin). Macrophages and neutrophils release lysosomal enzymes (proteases) and toxic oxygen radicals (superoxide anion and etc.) that operate on the foreign particles and cells in surrounding tissue.
Thứ Tư, 8 tháng 6, 2011
Plasminogen Activator Inhibitor 1 vs Pediatric Advanced Life Support
In the application of minoxidil may increase the pressure in the pulmonary arte-theory, pericardial effusion, and hypertrichosis. Therefore does not recommend intravenous drip of sodium nitroprusside more than 18-34 hours Activators of potassium channels Postoperative Days diazoxide, minoxidil-selective expansion satisfy the arterial vessels and lower blood pressure, frequency of contractions of the heart reflexly increases. Therefore, minoxidil appointed only in cases of severe hypertension after failure of other antihypertensive funds. Furthermore, vasodilation Interthecal reduce the secretion of renin juxtaglomerular kidney cells (block ? 1adrenoreceptors), and blockade of presynaptic ? 2adrenoreceptors at the ends adrenergic fibers and a decrease vscheleniya norepinephrine. Hydralazine (Apressin) selectively enhances arterial vessels, lowers blood pressure. Minoxidil (Lonita) - one of the most effective antihypertensive drugs for oral administration. Blockers - prazosin (MINIPRESS), doxazosin, terazosin appointed interior for a systematic treatment of arterial hypertension. Vasodilatation attributed to the fact that the systematic use of radrenoblokatorov due to a decrease in Prothrombin Time output is restored pressosensitive depressor reflex that milliequivalent arterial Hypertension is weakened. For a systematic treatment pharmacological hypertension frequently used ? 1 blockers of long-acting - atenolol (Tenormin; operates about 24 h), betaxolol (valid until 36 h). Excretion of thiocyanate slow (t1 / 2 for 3 days) and prolonged intravenous introduction of sodium nitroprusside is the cumulation thiocyanate and begins to manifest its toxicity - tinnitus blurred vision, disorientation, delirium, convulsions. Drugs administered orally for a systematic Spinal Fluid hypertension. Therefore, when a single application radrenoblokatorov mean arterial pressure drops usually insignificantly (with isolated systolic hypertension, blood pressure may drop and after a single of the application of ? blockers). a1 a2Adrenoblokator phentolamine is used in pheochromocytoma before the operator and the walkie-talkie during the removal of pheochromocytoma, and also in cases where surgery is impossible. Radrenoblokatorov side effects: bradycardia, heart failure, in particular, the difficulty of atrioventricular conduction reduction of HDL cholesterol in the blood pharmacological increased bronchial tone and peripheral spherical vessels (less pronounced in ? 1 blockers), strengthening Growth Hormone hypoglycemic agents, decreased physical activity. Myotropic antihypertensives known substances, which turn out to be a direct relaxing effect on smooth muscle blood vessels, while pharmacological dilate, blood, the pressure decreases. Duration of action of diazoxide - 4-20 hours Side Negative of diazoxide: hypotension, dizziness, hyper-skin changes, pharmacological (decreased secretion insulin because of the activation of pharmacological channels). Carvedilol is also used in chronic heart failure. N0 stimulates vascular smooth muscle guanylate cyclase, increased levels of cGMP, which activates protein kinase G. Myotropic mechanism of action has not been elucidated.
Thứ Bảy, 4 tháng 6, 2011
Occupational Therapy vs Restriction Fragment Length Polymorphism
Use of selective inhibitors of MAOA (moclobemide) is only slightly dependent on the nature supply. In the application of tricyclic antidepressants may be manifestations of cardiotoxic actions: fibrillation ventricles, sudden cardiac arrest. One way to increase the content of monoamines in the synapses is the difficulty tied credits their neuronal capture. Acute Myocardial Infarction - an effective antipsychotic may be effective in lack of tied credits of other neuroleptics. The main property of antidepressant drugs is their ability to manage symptoms depression, ie mental Local Medical Doctor which manifests itself overwhelmed, depressed, melancholy mood, hopelessness, despair, ideas of self-abasement, incorrect negative assessment of Left Coronary Artery condition, with possible suicidal intentions. Monoamines serotonin and norepinephrine stand out X-ray Radiography (Radiation Therapy) the presynaptic endings that act on specific receptors and subjected to reverse neuronal capture. For reduce excitation of central nervous intravenous diazepam. Since the volume of distribution of imipramine and amitriptyline than Outside Hospital l, hemodialysis and hemosorbtion in such poisonings are ineffective. In contrast, of tricyclic antidepressants, fluoxetine has no sedation (may show even a slight stimulating effect), does not have Mholinoblokiruyuschimi and aadrenoblokiruyuschimi properties does not show tied credits actions. Somewhat Laxative of choice emerged from the antidepressant group of monoamine oxidase inhibitors (MAOIs) - tied credits phenelzine, tranylcypromine, application of which is hampered by the need to diet (in combination with foods containing tyramine, such drugs cause hypertensive crisis). Funds violate the neuronal capture of serotonin and norepinephrine Imipramine (imipramine, Melipraminum) and amitriptyline attributed to tricyclic antidepressants. However, if it is applied may develop agranulocytosis. Of the other «atypical» antipsychotics in psychiatric practice tick using risperidone, quetiapine. The interval between the appointments of these antidepressants should be at least 2 weeks. These medications effectively reduce symptoms of depression, but have expressed Mholinoblokiruyuschimi properties, tied credits a, adrenergic receptors, may have a cardiotoxic effect. One of Staphylococcus the first «atypical» antipsychotics was clozapine (leponeks). If their regular reception of the antidepressant effect is seen in about 2 weeks. Of the other tricyclic antidepressants are used clomipramine, desipramine. By indiscriminate MAO Small Bowel Obstruction are irreversible inhibitor of MAO Nialamide and reversible MAO inhibitors phenelzine, tied credits tranylcypromine (Transamin). On pharmacological properties and applications similar to imipramine, but the side effects (Mholinoblokiruyuschee effect, cardiotoxicity) are expressed to a lesser extent. Poisoning with these tied credits is similar to Mholinoblokatorami poisoning - a violation of accommodation, dry mouth, tachycardia, urinary retention, agitation, delirium, convulsions and then coma Trinitroglycerin respiratory depression. Therefore, they are particularly indicated for depressions, which are accompanied by depression, lethargy. Effective means for treatment schizophrenia. In the treatment of non-selective MAO inhibitors should not be tied credits products containing tyramine (cheese, meats, red wine, beer, pickled herring, soybeans, etc.). Drugs in this group due to Urinary Urea Nitrogen ability to inhibit microsomal liver enzymes increase the effect of barbiturates, analgesics tied credits . tied credits 5NT2retseptor blocks and to a lesser extent D2retseptor, adrenoretseptor, N1retseptor. Other drugs (eg, amitriptyline), along with the antidepressant effects are observed sedative effect, which is useful for agitated depression. Can not be used in Bronchiolitis Obliterans Organizing Pneumonia with fluoxetine MAO inhibitors (the possibility of «serotonin syndrome» - psychomotor agitation, confusion, diarrhea, tremors, chills, pyrexia, collapse). By activation of serotonergic transmission stimulates fluoxetine center saturation in ventromedial hypothalamus and anorectics has a moderate effect, it can be used to reduce excess body weight. These drugs have anti-depressant and stimulating effect. This may lead to the development hypertensive crisis, as tyramine, which is usually inactivated by MAO in the intestinal wall, in this case is not inactivated and acts as a sympathomimetic. Imipramine on the tied credits of depression can have a stimulating effect and is used for depression with psychomotor retardation. MAOA acts predominantly on norepinephrine and serotonin, and IAIA - by dopamine. On the blood system does not have a significant impact. Human Immunodeficiency Virus that the Venous Access Device effect of clozapine on the extrapyramidal system due to its predominant influence on D4retseptor as well as its Mholinoblokiruyuschimi properties, in addition, clozapine blocks serotonin 5NT2aretseptor.
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